Blockade of brain alkaline phosphatase efficiently reduces amyloid-β plaque burden and associated cognitive impairment.

Marginal significance was considered at # P ≦ 0.08.

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Only a marginally significant increase in the number of entries in the APP/PS1 +/− mice was detected compared to WT mice.

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This increase was marginally statistically significant when all groups were compared but reached statistical significance when compared only with WT mice (Fig. 1 H).

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