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High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains.

J Virol · 2024 · PMC11494878 · PMID 39315814

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a slight trendno p-value reported
There was a slight trend for the first-time vaccinees to have higher titers than the previous-year vaccinees at 30 days post-vaccination, particularly against 5a.2 clade strains, but by 182 days post-vaccination the differences had mostly disappeared.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.