A Multi-Center Observation Study on Medication-Related Osteonecrosis of the Jaw (MRONJ) in Patients with Osteoporosis, and Other Non-Malignant Bone Diseases, in Northwestern Italy over 16 Years.

Biomedicines · 2024 · PMC11505559 · PMID 39457492

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an increasing trendno p-value reported

On the other hand, in this study among patients with non-malignant diseases throughout the 16-year period of investigation, we found an increasing trend emerging, with a median of 11.5 (range 0–14) yearly MRONJ cases in the 2007–2014 period, which increased to 15.1 (range 7–21) yearly MRONJ events in the 2015–2022 period.

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