Trp53 Deletion Promotes Exacerbated Colitis, Facilitates Lgr5+ Cancer Stem Cell Expansion, and Fuels Tumorigenesis in AOM/DSS-Induced Colorectal Cancer.

Int J Mol Sci · 2024 · PMC11507199 · PMID 39456736

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a slight trendno p-value reported

Immunofluorescence on colorectal adenocarcinomas from Trp53+/+ and Trp53−/− mice ( Figure S8 ) showed a slight trend towards increased vimentin in Trp53−/− tumors, but no significant differences in epithelial vimentin staining were detected.

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