Response Surface Methodology Optimization of Exosome-like Nanovesicles Extraction from <i>Lycium ruthenicum</i> Murray and Their Inhibitory Effects on Aβ-Induced Apoptosis and Oxidative Stress in HT22 Cells.

Foods · 2024 · PMC11507227 · PMID 39456390

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hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp ≤ 0.0001actually significant

The impact of each factor on the model is considered highly significant ( p ≤ 0.0001), and according to the F-values, the order of the influence of extraction conditions on LRM-ELN yield is as follows: A (concentration of PEG6000) > B (relative centrifugal force) > C (incubation time), indicating that the concentration of PEG6000 is the key factor affecting the yield.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Response Surface Methodology Optimization of Exosome-like Nanovesicles Extraction from &lt;i&gt;Lycium ruthenicum&lt;/i&gt; Murray and Their Inhibitory Effects on Aβ-Induced Apoptosis and Oxidative Stress in HT22 Cells.

The sentences

Response Surface Methodology Optimization of Exosome-like Nanovesicles Extraction from <i>Lycium ruthenicum</i> Murray and Their Inhibitory Effects on Aβ-Induced Apoptosis and Oxidative Stress in HT22 Cells.