Blood-Based Biomarkers in Alzheimer's Disease: Advancing Non-Invasive Diagnostics and Prognostics.

Int J Mol Sci · 2024 · PMC11507237 · PMID 39456697

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a decreasing trendno p-value reported

[ 70 ] revealed a decreasing trend in neuron-derived exosomes containing SNAP-25 in plasma, which correlated with cognitive status as measured by the Mini-Mental State Examination (MMSE).

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an increasing trendno p-value reported

Studies have demonstrated an increasing trend in CSF SNAP-25 levels in the AD population, while a decreasing index in the cerebral cortex indicates the extent of synaptic dysfunction [ 68 ].

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