A Population-Based Analysis of the Cancer Incidence in Individuals under 50 in a Northern Italian Province: Focusing on Regional Disparities and Public Health Implications.

In the age groups of 50–69 years (screening interval) and 70+, a decreasing trend was observed, with only a slight increase in 2021, following the resumption of screening activities after the suspension during the COVID-19 emergency.

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Although the cancer incidence predominantly rises in individuals over 50, a 2022 review highlights that an increasing trend is observed in those under 50 [ 3 ], particularly for cancers of the breast, colorectal, endometrium, bladder, and esophagus.

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Thyroid cancer also presents an interesting trend, characterized by a global APC of 1.9, which was confirmed in Italy by an increase in females (APC 3.5), in stark contrast to the significant decline observed in Reggio Emilia starting from 2014 (−10.2).

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