marginally significantp = 0.07
Upon further consideration of confounders in Mode 3, 1–2 cups/day of total coffee or caffeinated coffee was still associated with a lower risk of constipation although it is marginally significant for total coffee (total coffee: OR 0.61, 95% CI 0.35–1.06, p = 0.07); caffeinated coffee: OR 0.57, 95% CI 0.35–0.95, p = 0.03).