Consistent with this result, a comparison of the C/D ratio distribution in our cohort with the literature data on IR-Tac from Thölking’s pivotal study [ 3 ] revealed that the mean C/D ratio for MeltDose tacrolimus was significantly greater than that of IR-Tac, and this indicated an overall trend toward slower metabolism.
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Renal Allograft Function and the Tacrolimus C/D Ratio: Insights from a Prospective Study on MeltDose Tacrolimus.
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Renal Function Outcomes The cohort exhibited stable eGFR levels in the first 3 months, followed by an increasing trend until month 12.