Ovariectomized rats untreated with estradiol showed an increasing trend in weight from around 350–370 g to 390–420 g, while sham and E2 groups displayed consistent weight change and a slight weight loss, respectively, implying the influence of estrogen on the weight change pattern.
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Bio-Calcium from Skipjack Tuna Frame Attenuates Bone Loss in Ovariectomy-Induced Osteoporosis Rats.
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