Nevertheless, we believe that this does not invalidate our findings, since it is apparent that in studies after the year 2000, the results point unanimously to the direction of AI in approximately 30% of patients with bThal, with an increasing trend with advancing age, a finding that reflects the burden of repeated transfusions on the functionality of the HPA axis.
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Adrenal Insufficiency in Patients with Beta Thalassemia: A Meta-Analysis.
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