Network Pharmacology Combined with Experimental Validation to Investigate the Mechanism of the Anti-Hyperuricemia Action of <i>Portulaca oleracea</i> Extract.

The serum-UA levels of mice in different treatment groups showed a decreasing trend after gavage administration, among which the positive control group and the HPO group showed excellent UA-lowering efficacy (*** p < 0.001); no statistically significant difference was observed in the comparison between the groups ( Figure 5 A).

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One-way ANOVA was used to analyze the significance of differences, and a value of p < 0.05 was considered statistically significant; highly significant differences were indicated at p < 0.01.

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