Association of modifiable risk factors with progression to dementia in relation to amyloid and tau pathology.

1 ), the risk of progression to dementia was significantly increased among A- MCI participants with higher compared to lower CAIDE scores (Cox aHR = 3.1, 95% CI 1.43–6.53, KM log-rank chi-square (ChiSq) = 8.1, p = 0.004), while in the A + MCI subgroup a statistical trend-level association was observed (Cox aHR = 1.3, 95% CI 0.98–1.7, KM log-rank ChiSq = 0.16, p = 0.7).

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