Barely Significant
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The VALTIVE1 study protocol: a study for the validation of Tie2 as the first tumour vascular response biomarker for VEGF inhibitors.

BMC Cancer · 2024 · PMC11515440 · PMID 39448911

Europe PMCDOI
1
hedged sentence
0.0540
closest p · 1.1× alpha
0.0540
boldest claim

The sentences

marginally significantp = 0.054so close (0.05 < p ≤ 0.1)
Tie2 defined vascular responders demonstrated an improved PFS HR of 0.56 compared to vascular non-responders, which was significant in univariate analysis ( p = 0.034) and marginally significant in multivariate analysis ( p = 0.054).

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