If the lower limit of the 95% CI for the APC/AAPC is greater than zero, the corresponding ASMR and ASDR show an increasing trend, and vice versa; if it includes 0, the IS burden owing to high LDL-C is stable.
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Temporal trends of the burden of ischemic stroke attributable to high low-density lipoprotein cholesterol in China from 1999 to 2019.
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The sentences
While the mortality and DALY rate of IS attributable to high LDL-C exhibited a first increasing and then a decreasing trend over time in women aged 80–84 years and older, reaching a peak during the period of 2000–2004.