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(-)-Epicatechin regulates endoplasmic reticulum stress and promotes ferroptosis in lung cancer cells via the PERK/eIF2α/ATF4 signaling pathway.

PLoS One · 2024 · PMC11527276 · PMID 39480832

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an increasing trendno p-value reported
Lung cancer has become a major public health problem in China, and the incidence rate has also shown an increasing trend in recent years [ 24 ], which has severely affected people’s quality of life.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.