Adult rat ultrasonic vocalizations and reward: Effects of propranolol and repeated cocaine administration.

In Experiment 4, the apparent cocaine CPP represented only a statistical trend, even with the saline and PROP pretreatment groups pooled (t 19 = 2.46, p = 0.0237; Figure 9(b) ).

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Although cocaine produced only a weak CPP (see above), when the relevant data were pooled (i.e., from Experiments 3 and 4), a highly significant CPP was seen even in the animals pretreated with propranolol, and no propranolol × cocaine interaction was detected.

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