Auditory N1 event-related potential amplitude is predictive of serum concentration of BPN14770 in fragile X syndrome.

Results Including both placebo and treatment groups in the analysis, there was a marginally significant positive correlation between the post-period 1 PK values and the N1 amplitude to the first stimulus (rho = 0.396, p = .055; N = 24 valid).

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Statistical analysis A Spearman rank correlation analysis was conducted to determine whether PK values correspond to a reduction in the N1 amplitude to the first stimulus in the habituation pair which demonstrated marginal significance in the original analysis of the EEG N1 ERP component (see Fig. 1 or Berry-Kravis et al.

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