Quadrivalent Conjugate Vaccine and Invasive Meningococcal Disease in US Adolescents and Young Adults.

11 , 12 Although the MenACWY vaccine has been effective in mitigating the risk of IMD, 12 assessing the population-level association of vaccination with IMD burden has proven challenging, in part due to a decreasing trend in IMD incidence among different age groups that began 8 years before the introduction of the vaccine program (eFigure 1 in Supplement 1 ).

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