Bioinformatic and clinical experimental assay uncovers resistance and susceptibility mechanisms of human glioblastomas to temozolomide and identifies new combined and individual survival biomarkers outperforming <i>MGMT</i> promoter methylation.

Ther Adv Med Oncol · 2024 · PMC11544758 · PMID 39525666

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

borderline significanceno p-value reported

In addition, depletion of the MYT1 gene in cancer cells led to increased TMZ-induced cytotoxicity 67 which agrees with our findings where this gene expression was negatively associated with GBM survival with borderline significance ( Supplemental Table S3 ).

also in 7,017 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.