The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets.

J Anim Sci Biotechnol · 2024 · PMC11545576 · PMID 39511673

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an increasing trendP < 0.10so close (0.05 < p ≤ 0.1)

The mRNA expression of AHR (an IAld ligand) and the Wnt/β-catenin target gene Cyclin D1 exhibited an increasing trend in IAld group (0.05 < P < 0.10, Fig. 6 f and g).

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a decreasing trendno p-value reported

The enzymes kynB ( P < 0.05) and tnaA ( P < 0.05) were significantly lower, and ALDH (0.05 < P < 0.10) showed a decreasing trend in diarrheal piglets compared to healthy piglets (Fig. 3 d–g).

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