Comparative Analysis of Commercial and Home-Made Media on RSPO1/S6R Axis in Organoids with Different Wnt Backgrounds: A Methodological Guide for the Selection of Intestinal Patient-Derived Organoids Culture Media.

Int J Mol Sci · 2024 · PMC11546270 · PMID 39519079

Europe PMC DOI

hedged sentence

0.0689

closest p · 1.4× alpha

0.0689

boldest claim

The sentences

a positive trendp = 0.0689so close (0.05 < p ≤ 0.1)

Surprisingly, compared to its corresponding media without WNT3A (BASAL), WNT3A-CM-RSPO1 significantly enhanced the expression of the CCND1 ( p = 0.0051) and c-MYC ( p = 0.0007) genes, while A+B only showed a positive trend compared to A ( p = 0.0689 and p = 0.1049, respectively) ( Figure 2 A).

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