Barely Significant
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Anodic Desulfurization of Heterocyclic Thiones - A Synthesis to Imidazoles and Analogues.

Org Lett · 2024 · PMC11555668 · PMID 39467169

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highly significantno p-value reported
pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY document-id-old-9 ol4c03413 document-id-new-14 ol4c03413 ccc-price Nitrogen-containing molecules, especially imidazoles, are highly significant in heterocyclic chemistry due to their diverse chemical properties and applications in agriculture and pharmacology. 1 − 3 Imidazole cores are crucial in biologically active compounds because they interact well with various enzymes and receptors. 4 Imidazolium salts are versatile and widely used as precursors for NHC ligands. 5 Imidazole is also the third most common structure on the WHO list of essential medicines. 6 Several methods exist for forming imidazole scaffolds. 7 , 8 However, these methods often suffer from low yields, hazardous chemicals, and harsh conditions.

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