Subsequently, we set the genome-wide significance threshold based on a significance level of 1/nSNPs (1/2337054 = 4.28E-07, -log10( P ) = 6.37) for significant associations and 0.05/nSNPs (0.05/2337054 = 2.14E-08, -log10( P ) = 7.67) for extremely significant associations.
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An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein dairy cows.
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