Interestingly, both experimental groups presented negligible circulating levels of IL-18 with a decreasing trend, and no differences were found between WT and NLRP3 −/− mice infected with T. crassiceps during 8 weeks of follow-up (Fig. 4 b).
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Endogenous innate sensor NLRP3 is a key component in peritoneal macrophage dynamics required for cestode establishment.
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