Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer's pathologies.

A preliminary assessment of pure LATE-NC versus ADNC + LATE-NC and ADNC + LATE-NC + LB pathology indicated that there was a trend for pure LATE-NC cases to be older at death, with a possible trend to have a higher frequency of comorbid hippocampal sclerosis (Table 2 ).

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