Real-time morphometric analysis of targeted therapy for neuroblastoma cells in monolayer and 3D hydrogels using digital holographic microscopy.

An increasing trend was also observed in these cells at day 10 of culture (24 h) in non-VN-added hydrogels with CLG compared with non-VN-added controls (mean irregularity = 0.31 vs. 0.22) ( Figure 3 D, lower graphs), reaching similar values as in VN-rich conditions (VN-rich CLG vs. control, mean irregularity = 0.36 vs. 0.32) without statistical significance ( Figures 3 E and 3Eiii).

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