However, 5 μM AcA led to a highly significant increase in adduct levels compared to the negative control at all time points and showed a concentration dependence (versus 0.1 μM) as well as time dependence (1 h versus 6 h, 24 h versus 48 h).
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Metabolic Activation of 2-Methylfuran to Acetylacrolein and Its Reactivity toward Cellular Proteins.
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