Acute exposure to diisopropylfluorophosphate in mice results in persistent cognitive deficits and alterations in senescence markers in the brain.

In the hippocampus, like the PFC, Cdkn1a (p21) was significantly decreased and Ccl8, Mmp-12, il1a were increased and there was a nonsignificant trend ( p > 0.1) toward an increase in tmp1 ( Figure 7B ).

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