Potential Therapeutic Effect of Sinigrin on Diethylnitrosamine-Induced Liver Cancer in Mice: Exploring the Involvement of Nrf-2/HO-1, PI3K-Akt-mTOR Signaling Pathways, and Apoptosis.

3.2 Effect of Sinigrin on Serum Hepatic Parameters The results depicted in Figure 2 revealed that there was a highly significant ( p < 0.01) increase in the serum concentrations of liver damage markers after exposure to DEN these include; ALT ( Figure 2 A), AST ( Figure 2 B), alkaline phosphatase (ALP) ( Figure 2 C), gamma-glutamyl transferase (GGT) ( Figure 2 D), lactate dehydrogenase (LDH) ( Figure 2 E), and alpha-fetoprotein (AFP) ( Figure 2 F).

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