Elderly persons were found to be less symptomatic with SCH as compared with younger persons. 63 64 65 A meta-analysis by Feller et al failed to show improvement in quality of life or thyroid-related symptoms with thyroxine in SCH patients. 53 Potential Risks of Treatment With an increasing trend toward screening asymptomatic individuals by TSH assay in the last two decades, there is a rise in diagnosis of SCH and prescription of thyroxine.
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Clearing the Skepticism about Subclinical Hypothyroidism: Is It Beneficial to Treat Patients with Thyroid-Stimulating Hormone >4.5 and <10 mIU/L?
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