Specific gut microbiome signatures predict the risk of acute ischemic stroke.

In addition, MDI showed an increasing trend from TIA to AIS groups compared with HC.

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In contrast, the abundance of Lachnospiraceae_UCG-004 , which exhibited a decreasing trend in the HC, TIA, and AIS groups, was significantly negatively correlated with the stroke risk factors D-dimer (ρ = −0.1393, p < 0.05) and Hcy (ρ = −0.1129, p < 0.05).

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