<i>B. vulgatus</i> ameliorates high-fat diet-induced obesity through modulating intestinal serotonin synthesis and lipid absorption in mice.

Blocking TRPV1 with capsazepine significantly reduced the 5-HT-induced increase of Isc in the jejunal epithelium of Control mice, while a decreasing trend was observed in the jejunal mucosal epithelium of mice colonized with B. vulgatus ( Figure 6g ), suggesting that TRPV1 is involved in 5-HT-induced jejunal substance transport.

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