Blind But Alive - Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish.

To determine the identity of these cells, we analyzed the expression of islet2b , a known marker of mature RGCs, 38 using qPCR, and found a highly significant downregulation in mutant retinae ( atoh7 +/+ : 1 ± 0.026, atoh7 −/− : 0.14 ± 0.018, n = 3; Fig. 3 B).

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