Infiltrating macrophages and CD4 + T cells tended to be higher in the kidneys of DMHFD mice compared to controls, but this did not achieve significance on multiple groups comparison, whereas dendritic cells were lower in DMHFD + Finerenone kidneys than controls (Fig. 2 A).
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Finerenone attenuates downregulation of the kidney GLP-1 receptor and glucagon receptor and cardiac GIP receptor in mice with comorbid diabetes.
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