Evidence suggests that there may be significant sex differences in both the pathophysiology of sepsis and kidney injury, as well as in the response to treatments like BBR [ 38 , 39 ].
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Berberine Mitigates Sepsis-Associated Acute Kidney Injury in Aged Rats by Preserving Mitochondrial Integrity and Inhibiting TLR4/NF-κB and NLRP3 Inflammasome Activations.
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