an increasing trendp = 0.0876
In addition, there was a significant reduction in the latency to the first immobility between the AAV-EGFP + Saline and AAV-TCF7L2 + Saline groups (t 28 = 2.053, p = 0.0495), and the AAV-TCF7L2 + Memantine group showed an increasing trend compared with the AAV-TCF7L2 + Saline group (t 28 = 1.770, p = 0.0876).