a trend towards significancep = 0.06
The use of b/tsDMARDs was significant in the SCORE2 algorithm in the listwise analysis [coefficient −0.006 (95% CI −0.011 to −0.0016) p = 0.010] and showed a trend towards significance in the computation analysis [coefficient −0.003 (95% CI −0.008 to 0.0002) p = 0.06] ( Table 4 ). 5.