Are the Common Genetic 3'UTR Variants in ADME Genes Playing a Role in Tolerance of Breast Cancer Chemotherapy?

Int J Mol Sci · 2024 · PMC11594993 · PMID 39596349

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0570

boldest claim

The sentences

highly significantp < 0.00001actually significant

Also, the presence of two or more risk factors resulted in a highly significant elevation of risk for severe vomiting (OR 15.97; 5.12–49.87; p < 0.00001) (The second table in Section 2.7 ).

also in 132,142 other papers

borderline significancep = 0.057so close (0.05 < p ≤ 0.1)

The RALPB1 rs12680 allele C (OR 2.05; 0.97–4.32; p = 0.057; result at borderline significance) and premenopausal age (OR 2.92; 1.11–7.65; p = 0.028) were correlated with a higher risk of early vomiting ( Table 5 ).

also in 7,017 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.