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Supplementation with Chinese herbal preparations protect the gut-liver axis of Hu sheep, promotes gut-liver circulation, regulates intestinal flora and immunity.

Front Immunol · 2024 · PMC11599181 · PMID 39606237

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a decreasing trendno p-value reported
an increasing trendno p-value reported
The results showed a decreasing trend in most bile acids, organic acids and their derivatives, heterocyclic compounds hormones and their related substances, and an increasing trend in amino acids and their metabolites, and carbohydrates.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.