The result of WB assay showed that the expression levels of ATG5, NCOA4 and Beclin1 were obviously decreased in the ZnO-NPs + Fer-1 group in contrast to the ZnO-NPs group, and the expression of p62 also showed an increasing trend (Fig. 6 C).
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Zinc oxide nanoparticles mitigate the malignant progression of ovarian cancer by mediating autophagy-dependent ferroptosis.
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