Succinate-producing microbiota drives tuft cell hyperplasia to protect against Clostridioides difficile.

J Exp Med · 2025 · PMC11602550 · PMID 39589553

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marginally significantno p-value reported

Mice treated with vancomycin showed significantly higher proportions of TCs in the colon by flow cytometry compared with mice receiving PBS (P = 0.005) and a marginally significant increase compared with metronidazole ( Fig. 1 C ).

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