"Quality over quantity:" smaller, targeted lesions optimize quality of life outcomes after MR-guided focused ultrasound thalamotomy for essential tremor.

Effect of skull density ratio, dose volume, lesion size, and normative tractographic coefficients on QoL outcomes Stratified by patient QoL assessment at last follow-up, the skull density ratio (SDR) of “worse” patients was highest (0.64 ± 0.03), followed by “better” (0.58 ± 0.02), and lastly “same” (0.53 ± 0.03), with the group differences trending toward significance (Kruskal-Wallis H = 4.7705, p = 0.09).

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