TbpB-based oral mucosal vaccine provides heterologous protection against Glässer's disease caused by different serovars of Spanish field isolates of Glaesserella parasuis.

parasuis field isolates, a highly significant protection was conferred by the vaccination in the survival rate ( p < 0.0001), regardless of G. parasuis TbpB cluster and SV, since all non-immunized piglets died within the initial three days post-infection (dpi) (Table 2 ).

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