Role of GSTM1 and GSTT1 Gene Polymorphisms on Lung Cancer Susceptibility and Effect on Platinum-Based Chemotherapy-Induced Toxicity in Bangladeshi Lung Cancer Patients.

In the second phase of this study, we found a nonsignificant trend toward an association between GSTM1 and GSTT1 gene polymorphisms and increased risk of platinum-based chemotherapy-induced toxicities like anemia, neutropenia, leukopenia, thrombocytopenia, and gastrointestinal toxicity in lung cancer patients ( Table 5 ).

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