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Diagnostic validation of the urine albumin-to-creatinine ratio for early renal disease in healthy dogs and dogs with chronic kidney disease.

J Vet Sci · 2024 · PMC11611491 · PMID 39608771

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an increasing trendno p-value reported
As the IRIS stage progressed, the CREA levels showed an increasing trend.

also in 63,971 other papers

a decreasing trendno p-value reported
As CKD progressed, the UAC, UPC, BUN, CREA, and SDMA levels tended to increase, while USG showed a decreasing trend ( Table 3 ).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.