Effects of glucokinase haploinsufficiency on the pancreatic β-cell mass and function of long-term high-fat, high-sucrose diet-fed mice.

Subsequently, at 60 weeks‐of‐age, β‐cell mass was further increased in Gck +/+ HFHS mice, and an increasing trend was also observed in Gck +/− HFHS mice (Figure 4d ).

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