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The global, regional, and national burden of urolithiasis in 204 countries and territories, 2000-2021: a systematic analysis for the Global Burden of Disease Study 2021.

EClinicalMedicine · 2024 · PMC11618031 · PMID 39640943

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a decreasing trendno p-value reported
Furthermore, the age-standardised DALY rate showed a decreasing trend across all SDI quintiles over the same period: high-middle SDI (−28.9% [–34.4 to −23.0]), middle SDI (−22.6% [–30.5 to −10.9]), and low-middle SDI (−2.9% [–15.8 to 12.9]).

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an increasing trendno p-value reported
Twelve GBD regions showed declining trends in the age-standardised incidence rate of urolithiasis between 2000 and 2021, and the remaining nine GBD regions had an increasing trend of age-standardised rates of urolithiasis.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.