Comparative analysis using the Hallmark gene sets collection and pairwise GSEA, similar to the relapse-based comparisons, highlights a highly significant statistical difference between PDS1 and PDS3 for MYC Targets V1 gene set (hereafter MYC V1; Fig. 4 B).
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Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data.
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