The IRDS genes identified in our RNA‐seq analysis are comparable with the previously observed signature, with highly significant, differential expression of genes including IFI6 , IFI27 , MX1 , BST2 and HERC6 in glioblastoma cells following co‐culture with microglia.
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Microglia induce an interferon-stimulated gene expression profile in glioblastoma and increase glioblastoma resistance to temozolomide.
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